Antimicrobial Activities of some Benzocoumarines and benzochromone
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Research Article
VOLUME: 9 ISSUE: 2
P: 59 - 62
December 2008

Antimicrobial Activities of some Benzocoumarines and benzochromone

Trakya Univ J Nat Sci 2008;9(2):59-62
1. Department of Chemistry, Faculty of Arts and Science, Trakya Universty, Edirne,
2. TÜBİTAK, UME, Department of Chemistry, P.Box. 54. Gebze-Kocaeli, Turkey
No information available.
No information available
Received Date: 20.05.2008
Accepted Date: 03.11.2008
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Abstract

Two benzocoumarins (1, 2) and a benzochromone (3) were obtained from the reaction of 2,7 dihydroxynaphthalene and ethyl acetoacetate in the presence of sulphuric acid (95-80 %) as a catalyst. These products were screened in order to assay their antimicrobial activies against standard bacterial strains such as E. coli ATCC 29995, S. S. aureus ATCC 6538P, Mycobacterum smegmatis and the yeast C. albicans ATCC 10239. Neither 1 nor 3 exhibited the antimicrobial activies against standard bacterial strains. The only 2 showed activity against S. S. aureus ATCC 6538P. Also, the antioxidant capacities of the compounds were investigated by using the CUPRAC method.

Keywords:
2, 7-Dihydroxynapthalene, ethyl acetoacetate, benzocoumarin, benzochromone, antimicrobial activity, the CUPRAC method.