Abstract

The role of oxidative stress in pathogenesis of many diseases has interested researchers in recent years. Erythrocytes are in contact with all organs and tissues and are one of the most vulnerable cell types against oxidative stress. Therefore, erythrocyte cells are commonly used in studies performed to reveal negative effects of oxidative stress. On the other hand, the number of studies carried out with the aim of finding natural antioxidants to reduce or neutralize negative effects of oxidative stress is increasing day by day. Plant extracts are mostly used in these studies and antioxidant effects of these extracts are investigated. In the present study, current data on the means of producing oxidative stress in erythrocytes and the plant extracts used against oxidative stress were reviewed.